Prevention of aortic valve stenosis through modulation of LXRb using saringosterol

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Prevention of aortic valve stenosis through modulation of LXRb using saringosterol

Session: Molecular mechanisms and therapeutic targets in aortic valve disease and calcification

Topic: Valvular Heart Disease

Speaker: Doctor M. Noethel (Bonn, DE)

Event: ESC Congress 2025

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Doctor Moritz Noethel

Heartcenter Bonn, University Hospital Bonn, Bonn (Germany)

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6 more presentations in this session

The K+ channel KCa3.1 promotes contraction in aortic stenosis valve myofibroblast cells

Speaker: Miss M. Whitfield (Leicester, GB)

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Novel ex-vivo calcification model for human aortic valves reveals patient-specific effect of compound.

Speaker: Ms M. El Ouraoui (Leiden, NL)

Glycolysis blockade reduces synthesis and maturation of glycoproteins as well as leukocyte adhesion in inflamed aortic valve cells

Speaker: Miss M. Peral-Rodrigo (Valladolid, ES)

Activation of cGMP-PKG signaling pathway attenuates aortic valve calcification through ULK1-mediated autophagy

Speaker: Doctor Y. Wang (Chengdu, CN)

Targeted modulation of sphingolipid signaling to inhibit the progression of aortic valve disease

Speaker: Doctor M. Benkhoff (Duesseldorf, DE)

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Molecular mechanisms and therapeutic targets in aortic valve disease and calcification

Speakers: Doctor M. Noethel, Miss M. Whitfield, Ms M. El Ouraoui, Miss M. Peral-Rodrigo, Doctor Y. Wang...

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About the event

ESC Congress 2025

29 August - 1 September 2025

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