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Novel ex-vivo calcification model for human aortic valves reveals patient-specific effect of compound.

Session: Molecular mechanisms and therapeutic targets in aortic valve disease and calcification
Topic: Valvular Heart Disease
Speaker: Ms M. El Ouraoui (Leiden, NL)
Event: ESC Congress 2025

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Ms Maroua El Ouraoui

Leiden University Medical Center, Leiden (Netherlands (The))
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7 more presentations in this session

The K+ channel KCa3.1 promotes contraction in aortic stenosis valve myofibroblast cells

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Prevention of aortic valve stenosis through modulation of LXRb using saringosterol

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The role of transcription factor junb in aortic valvular interstitial cell calcification

Speaker: Doctor C. Song (Chengdu, CN)

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Glycolysis blockade reduces synthesis and maturation of glycoproteins as well as leukocyte adhesion in inflamed aortic valve cells

Speaker: Miss M. Peral-Rodrigo (Valladolid, ES)

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Activation of cGMP-PKG signaling pathway attenuates aortic valve calcification through ULK1-mediated autophagy

Speaker: Doctor Y. Wang (Chengdu, CN)

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Access the full session

Molecular mechanisms and therapeutic targets in aortic valve disease and calcification

Speakers: Ms M. El Ouraoui, Miss M. Whitfield, Doctor M. Noethel, Doctor C. Song, Miss M. Peral-Rodrigo...
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ESC Congress 2025

29 August - 1 September 2025

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