AAV-mediated gene therapy improves cardiac function in humanized PLN-R14del mice: a preclinical model of PLN-R14del induced cardiomyopathy

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AAV-mediated gene therapy improves cardiac function in humanized PLN-R14del mice: a preclinical model of PLN-R14del induced cardiomyopathy

Session: Molecular and immune mechanisms in cardiomyopathy

Topic: Gene Therapy, Cell Therapy

Speaker: Miss K. Gaar-Humphreys (Utrecht, NL)

Event: ESC Congress 2025

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About the speaker

Miss Karen Gaar-Humphreys

University Medical Center Utrecht, Utrecht (Netherlands (The))

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Cardiac myosin inhibitor MYK-581 prevents development of hypertrophic cardiomyopathy phenotype in human iPSC models

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Molecular and immune mechanisms in cardiomyopathy

Speakers: Miss K. Gaar-Humphreys, Associate Professor B. Gerull, Mr E. Zulfaj, Doctor S. Graeger, Professor B. Knollmann

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ESC Congress 2025

29 August - 1 September 2025

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