Cardiac myosin inhibitor MYK-581 prevents development of hypertrophic cardiomyopathy phenotype in human iPSC models

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Cardiac myosin inhibitor MYK-581 prevents development of hypertrophic cardiomyopathy phenotype in human iPSC models

Session: Molecular and immune mechanisms in cardiomyopathy

Topic: Cardiomyopathies

Speaker: Professor B. Knollmann (Nashville, US)

Event: ESC Congress 2025

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Professor Bjorn Knollmann

Vanderbilt University Medical Center, Nashville (United States of America)

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Sex-specific effects of oestrogen in Takotsubo syndrome: protective in females, detrimental in males

Speaker: Mr E. Zulfaj (Gothenburg, SE)

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AAV-mediated gene therapy improves cardiac function in humanized PLN-R14del mice: a preclinical model of PLN-R14del induced cardiomyopathy

Speaker: Miss K. Gaar-Humphreys (Utrecht, NL)

The interleukin-6/glycoprotein 130 pathway in cardiomyocytes contributes to the pathogenesis of sepsis-induced cardiomyopathy

Speaker: Doctor S. Graeger (Greifswald, DE)

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Molecular and immune mechanisms in cardiomyopathy

Speakers: Professor B. Knollmann, Associate Professor B. Gerull, Mr E. Zulfaj, Miss K. Gaar-Humphreys, Doctor S. Graeger

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ESC Congress 2025

29 August - 1 September 2025

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