ESC 365 - The KCa2 channel inhibitor AP14145, but not dofetilide or ondansetron, provides functional atrial selectivity in guinea pig hearts

ESC Premium Access

The KCa2 channel inhibitor AP14145, but not dofetilide or ondansetron, provides functional atrial selectivity in guinea pig hearts

Session: Poster Session 1 - Preclinical pharmacotherapy

Topic: Antiarrhythmic Pharmacotherapy

Speaker: Associate Professor N. Edvardsson (Gothenburg, SE)

Event: ESC Congress 2019

Congress Presentation

Add to my library

About the speaker

Associate Professor Nils Edvardsson

Sahlgrenska University Hospital, Gothenburg (Sweden)

0 follower

8 more presentations in this session

Mechanisms of action of the small conductance Ca2+-activated K+-channel modulator AP30663, a novel compound being developed for treatment of atrial fibrillation in man

Speaker: Mrs S. Bomholtz (Copenhagen N, DK)

The SK channel inhibitor AP30663, converts vernakalant-resistant persistent AF and prevents its reinduction in pigs

Speaker: Doctor J. Diness (Copenhagen, DK)

The role of a phosphoinositide-3 kinase inhibitor in vascular inflammation

Speaker: Miss H. Chaudhry (London, GB)

Anti-thrombin nanoparticles for reduce vascular damage and promote functional recovery in acute ischemic kidney injury well after reperfusion

Speaker: Associate Professor H. Pan (Saint Louis, US)

The small conductance Ca2+-activated K+-channel inhibition tool compound AP14145 protected the guinea pig heart from ventricular arrhythmia during hypokalemia whereas dofetilide was pro-arrhythmic

Speaker: Professor M. Grunnet (Copenhagen N, DK)

Access the full session

Poster Session 1 - Preclinical pharmacotherapy

Speakers: Associate Professor N. Edvardsson, Mrs S. Bomholtz, Doctor J. Diness, Miss H. Chaudhry, Associate Professor H. Pan...

About the event

ESC Congress 2019

31 August - 4 September 2019

Sessions Presentations

Congress

ESC 365 is supported by

Explore sponsored resources

Explore sponsored resources