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Platelet responsiveness to PAR4 activation in a healthy population and its inhibition by a potent and selective PAR4 antagonist

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About the speaker

Doctor Kate Downes

Cambridge (United Kingdom of Great Britain & Northern Ireland)
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6 more presentations in this session

The platelet protease-activated receptor-4 antagonist, UDM-002555, alone and in combination with aspirin inhibits arterial thrombosis with limited impact on hemostasis in cynomolgus monkeys

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Can off-pump coronary artery bypass graft surgery be performed 3 days after clopidogrel discontinuation without increasing the bleeding risk in acute coronary syndrome patients?

Speaker: Mr W. Liu (Beijing, CN)

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Evaluation of immature platelet parameters as compared to established predictors of platelet reactivity after thienopyridine loading

Speaker: Doctor C. Stratz (Bad Krozingen, DE)

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Impact of diabetes mellitus on the pharmacodynamic effects of ticagrelor versus clopidogrel in troponin-negative acute coronary syndrome patients undergoing ad-hoc percutaneous coronary intervention

Speaker: Professor J. Sweeny (New York City, US)

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Large mean platelet volume is associated with impaired clopidogrel-responsiveness in acute coronary syndrome patients, with no impact on prasugrel or ticagrelor effects

Speaker: Doctor A. Marcano Fernandez (L'hospitalet De Llobregat, ES)

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Mechanisms of platelet activation

Speakers: Doctor K. Downes, Doctor P. Wong, Mr W. Liu, Doctor C. Stratz, Professor J. Sweeny...
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ESC Congress 2016

27 August - 31 August 2016

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