PDE1 inhibition potentiates arrhythmogenic disturbances in calcium homeostasis and electrical activity induced by pathological adenosine levels in mouse ventricular myocytes

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PDE1 inhibition potentiates arrhythmogenic disturbances in calcium homeostasis and electrical activity induced by pathological adenosine levels in mouse ventricular myocytes

Session: Molecular and genetic mechanisms of arrhythmias: from calcium dysregulation to syndromic signatures

Topic: Arrhythmias

Speaker: Mrs C. Aceituno (Barcelona, ES)

Event: ESC Congress 2025

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About the speaker

Mrs Cristina Aceituno

Biomedical Research Institute Barcelona IIBB-CSIC, Barcelona (Spain)

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6 more presentations in this session

Synapsin 2 deficiency impairs NCX1 transport and increases susceptibility to ventricular arrhythmias and heart failure mortality

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Speaker: Miss I. Rugolo (Oslo, NO)

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Speaker: Mr K. Hernandez Lopez (Madrid, ES)

Peptide array-derived optimized secretoneurin variants enhance CaMKII inhibition and reduce pathological cardiomyocyte Ca2+ handling

Speaker: Miss I. Rugolo (Oslo, NO)

Genetic analysis and electrocardiographic patterns in Brugada syndrome

Speaker: Miss M. Modena (Pisa, IT)

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Molecular and genetic mechanisms of arrhythmias: from calcium dysregulation to syndromic signatures

Speakers: Mrs C. Aceituno, Doctor A. Ottesen, Miss I. Rugolo, Mr K. Hernandez Lopez, Miss I. Rugolo...

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ESC Congress 2025

29 August - 1 September 2025

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