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Novel first-in-class drug candidate protects from ischemia-reperfusion injury by targeting the SERCA2 complex

Session: Innovative therapeutic strategies to combat ischaemia-reperfusion injury and cardiac dysfunction
Topic: Ischaemia, Infarction, Cardioprotection
Speaker: Mrs A. Calejo (Oslo, NO)
Event: ESC Congress 2025

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Mrs Ana Calejo

Serca Pharmaceuticals, Oslo (Norway)
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6 more presentations in this session

PPAR alpha-driven CISD2 upregulation by hesperetin protects against myocardial ischemia/reperfusion injury

Speaker: Professor C. Yeh (Tao-Yuan, TW)

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Empagliflozin preserves hemodynamics and left ventricular function in nephrectomized rats after ischemia-reperfusion injury: a potential direct cardioprotective effect of SGLT2 inhibitor

Speaker: Doctor K. Akiyoshi (Kasukabe, JP)

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Organic polydopamine nanoparticles ameliorate endothelial ischemia-reperfusion injury, increasing antioxidant defense and reducing inflammatory response

Speaker: Doctor S. Babboni (Pisa, IT)

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Activation of AMPK via inhibition of PAR2 limits myocardial ischemia-reperfusion injury

Speaker: Doctor L. Li (Winnipeg, CA)

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Mitochondria-targeted Hydrogen Sulfide exerts protective effects and maintains mitochondria homeostasis against ischemia reperfusion injury in heart transplantation via the mitofusion-1 pathway

Speaker: Doctor C. Zhu (Changchun, CN)

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Innovative therapeutic strategies to combat ischaemia-reperfusion injury and cardiac dysfunction

Speakers: Mrs A. Calejo, Professor C. Yeh, Doctor K. Akiyoshi, Doctor S. Babboni, Doctor L. Li...
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ESC Congress 2025

29 August - 1 September 2025

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