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Preclinical characterisation and first-in-human results on the tolerability and pharmacodynamic effect of REGN9933, a monoclonal antibody targeting the factor XI/activated factor XI apple 2 domain

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Doctor Aaron Kithcart

(United States of America)
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First-in-human study to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of RBD4059, a GalNAc-siRNA drug targeting coagulation factor XI (FXI), in healthy subjects

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Access the full session

Biotherapies in cardiovascular disease: from bench to bedside

Speakers: Doctor A. Kithcart, Professor M. Holinstat, Doctor P. Jain, Doctor A. Gabrielsen, Doctor X. Chen...
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ESC Congress 2024

30 August - 2 September 2024

Sessions Presentations