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Doctor Roger J Hajjar

Mass General Brigham, Boston (United States of America)

Member of:

European Society of Cardiology
Heart Failure Association of the ESC

Dr. Roger Hajjar is the Director of the Gene and Cell Therapy Institute at Mass General Brigham in Boston, Massachusetts. He has been at the forefront of the development and translation of cardiac gene therapy from early-stage research through to clinical trials. Under his leadership, his laboratory has identified and validated multiple cardiac therapeutic targets, which have culminated in the successful initiation and completion of First-in-Human gene therapy clinical trials for patients suffering from various forms of heart failure and cardiomyopathies. Dr. Hajjar is the co- founder of several gene therapy enterprises, including Nanocor/AskBio and Medera, which are actively advancing therapeutic programs targeting both rare and prevalent forms of cardiomyopathy.

NAN-CS101: A first-in-human Phase 1 open-label dose-escalation study of AB-1002 gene therapy for the treatment of NYHA class III heart failure

Event: Heart Failure 2025

Topic: Treatment

Session: Late-breaking clinical trials in chronic heart failure

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Gene therapy for heart failure

Event: Heart Failure 2018

Topic: Signal Transduction, Mechanotransduction

Session: Positive inotropy - Still an approach we should go for?

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Gene therapy to target calcium cycling in heart failure.

Event: ESC Congress 2017

Topic: Ion channels and electrophysiology

Session: Keep calcium signalling under control to prevent heart failure

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Genome engineering of iPS-derived cardiomyocytes.

Event: ESC Congress 2017

Topic: Genetics and gene therapy

Session: Should we modify the genome to cure cardiovascular disease?

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Role of calcium signalling in diastolic dysfunction

Event: ESC Congress 2016

Topic: Echo-ventricular function

Session: Diastology: from cellular signalling to advanced imaging techniques

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