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Doctor Matteo Elia Mangoni

Institute of Functional Genomics, University of Montpellier, Montpellier (France)

Our research team focuses on the cellular mechanisms underlying the genesis and control of cardiac automaticity. In the past, we have introduced the use of genetically-modified mice in the study of pacemaker activity and described the role of L-type Cav1.3 and T-type Cav3.1 calcium channels in cardiac automaticity and coduction in mice and humans. Our group now studies the complex interactions between ion channels of the plasma membrane and intracellular pathways underlying pacemaking, as well as their impact in diseases of cardiac automaticity.

Ion channel (dys)function and regulation

Event: EHRA 2019

Topic: Cardiac Diseases

Session type: Symposium

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Regulation of cardiac ion channels

Event: EHRA EUROPACE - CARDIOSTIM 2017

Topic: Cellular Electrophysiology

Session type: Featured Symposium

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