Cardiovascular Research Institute Maastricht (CARIM), Maastricht (Netherlands (The))
Member of:
Stef Zeemering is a researcher with a strong interest in atrial signal analysis and the genetics of atrial fibrillation. He has developed many tools for the processing and analysis of high-density contact mapping of AF in animal models and patients. More recently he has been developing a systems biology approach to the understanding of AF, by combining patient genotype, atrial gene expression, atrial tissue characteristics on the one hand, and clinical patient phenotype and ECG features on the other, to arrive at an improved and more mechanism-based classification of AF.
Atrial fibrillation in the presence or absence of heart failure is associated with differential expression of genes involved in inflammation, hypertrophy, cardiomyocyte structure and fibrosis