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Doctor Saumya Das

Massachusetts General Hospital - Harvard Medical School, Boston (United States of America)

Member of:

European Society of Cardiology

Saumya Das, MD, PhD is a Professor of Medicine at Harvard Medical School, a faculty member of the Cardiac Arrhythmia Service and the co-Director of the Arrhythmia Genetics Clinic at Massachusetts General Hospital. He graduated summa cum laude in Biology from Harvard College. He completed his MD-PhD training at Harvard Medical School with his PhD in neurobiology in 2000. Following residency in internal medicine and fellowship training in cardiovascular disease and clinical cardiac electrophysiology at MGH. His research has focused on extracellular vesicles and their cargo RNAs as biomarkers in cardiometabolic disease, functional characterization of non-coding RNAs in heart disease, and RNA-based therapeutics. He has served as a co-chair of the steering committee of the NIH Extracellular Communication Consortium. He was inducted in the American Society of Clinical Investigation in 2020 and received an NIH EIA award. He is the co-founder of Thryv Therapeutics.

THRV-1268, a novel and potent SGK1 inhibitor, improved adverse cardiac remodeling beyond empagliflozin, an SGLT2 inhibitor, by reducing inflammation and fibrosis mechanisms in heart failure.

Event: ESC Congress 2025

Topic: Heart Failure with Reduced Ejection Fraction (HFrEF)

Session: SGLT2 inhibitors in heart failure: prevention and treatment

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