THRV-1268, a novel and potent SGK1 inhibitor, improved adverse cardiac remodeling beyond empagliflozin, an SGLT2 inhibitor, by reducing inflammation and fibrosis mechanisms in heart failure.
Event:
ESC Congress 2025
Topic:
Heart Failure with Reduced Ejection Fraction (HFrEF)
Session:
SGLT2 inhibitors in heart failure: prevention and treatment