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Doctor Steven Lisgo

Newcastle University, Newcastle-Upon-Tyne (United Kingdom of Great Britain & Northern Ireland)

Having relied heavily upon the unique materials provided by the Human Developmental Biology Resource (HDBR; www.hdbr.org) for his PhD studies in craniofacial development, Dr Lisgo took over as manager of the resource in 2007. Since that time, the HDBR has seen a large expansion from collecting around 50 human fetal samples per year to more than 300. HDBR also hosts the HDBR Atlas (www.hdbratlas.org) - a website dedicated to early human development as well as being a repository for gene expression in human embryonic/fetal tissues. In addition, the HDBR provide access to various gene expression analysis services, including spatial transcriptomics. Along with colleagues at Newcastle University, Dr Lisgo establish SpaRTAN (Spatially Resolved Transcriptomics At Newcastle; https://www.ncl.ac.uk/bsu/spartan/) – a complete end-to-end spatial transcriptomics analysis service, and was the first group in Europe to be accredited as a certified service provider with 10X Genomics in 2020.

Spatial transcriptomics reveals novel genes during the remodelling of embryonic human arterial valves

Event: Frontiers in CardioVascular Biomedicine 2024

Topic: Valvular Heart Disease

Session: Bed to bench and back: mechanisms in valve formation and disease

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