Florian Wenzl, MD FESC completed his postgraduate training at the University of Pennsylvania and continued his cardiology fellowship at the German Heart Centre before joining the University of Zurich in 2021. Florian and his team focus on cardiovascular risk prediction and aim to identify novel molecular targets/biomarkers to refine personalised treatment strategies. He developed the GRACE 3.0 score for early patient stratification and cardio-metabolic risk algorithms for optimized residual cardiovascular risk management. Florian is involved in various clinical trials investigating new translational treatment approaches, funded by the European Union and other bodies. For his efforts in research and teaching, he received various notable awards. Florian is part of the UK Disease Registration and Analysis Service and the Karolinska Institutet, and serves on the ESC Committee on Digital Cardiology & AI and the steering committee of the Swiss National Registry of Myocardial Infarction.